Model-Based Systems Engineering or MBSE (Model-Based Systems Engineering*) is a systems engineering methodology that focuses on the creation and exploitation of domain models as the primary means of information exchange, rather than focusing on document-based information exchange.[1][2]​.

Specifically, according to INCOSE, the MBSE methodology is the "formalized application of modeling to assist in system requirements, design, analysis, verification and validation activities that begin in the conceptual design phase and continue during development and subsequent phases of the life cycle."[1]​[3]​.

The MBSE methodology is commonly used in industries such as aerospace, railways, automotive, defense, etc.[4][5][6][7]​.

In 1993, Wymore, A. Wayne coined the term "model-based systems engineering" in his book of the same name.[8]​.

In January 2007, the MBSE approach began to gain popularity when INCOSE introduced its “MBSE Initiative.” The objectives included achieving greater productivity by minimizing unnecessary manual transcription of concepts during the coordination of the work of large teams. The MBSE approach is described in INCOSE's "MBSE Vision 2020", with a methodology focused on the management of distributed but integrated models.[1]​.

Starting in 2014, the approach also began to cover aspects related to model execution in computer simulation experiments, to bridge the gap between system model specifications and the corresponding simulation software. Consequently, along with MBSE, the term "modeling and simulation-based systems engineering" or M&SBSE (acronym for modeling and simulation-based systems engineering) has also been used.[9]​.

INCOSE organizes an annual meeting on MBSE, which has different sections and working groups.[1]​.

• - AUTOSAR (AUTomotive Open System ARchitecture).

• - Model-driven engineering (MBD).

• - Object Management Group.

• - Systems engineering.

• - SysML - Systems Modeling Language.

• - Unified Modeling Language (UML).